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課程名稱 |
高等化學生物學一
ADVANCED CHEMICAL BIOLOGY(I) |
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開課學期 |
96-1 |
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授課對象 |
理學院 化學研究所 |
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授課教師 |
方俊民 |
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課號 |
Chem7035 |
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課程識別碼 |
223 M1610 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
必修 |
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上課時間 |
星期一6(13:20~14:10)星期三5,6(12:20~14:10) |
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上課地點 |
化217化217 |
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備註 |
限碩士生修習。本課程中文授課,使用英文教科書。與陳振中、林俊宏合開
總人數上限：50人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/961AdvChemBiol_1 |
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課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
Molecules of Life
1. Protein Folding and
Misfolding
2. Biological Membranes
3. Membrane Proteins
4. Carbohydrates
Structural Determination and
Sequencing of Biomolecules
1. Overview of Chemical
Biology
2. Struct. Determ. of Small
Molecules
3. Struct. Determ. &
Sequencing of Proteins
4. Struct. Determ. &
Sequencing of Nucleic Acids
5. Struct. Determ. &
Sequencing of Carbohydrates
Enzyme Mechanism and
Functionc
1. Biosynthesis and
Metabolism
2. Chemical Catalysis
Related to the Biological
System
3. Common Mechanisms and
Transformations in
Biological Chemistry
4. Basics of Enzyme Kinetics
5. Practical kinetic and
Spectrometric Methods
6. Special Topics in
Bioorganic Chemistry
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課程目標 |
The students in this course
will be grouped into several
teams. In principle, a team
will consist of 3–6
students from different
disciplines to work
together. Each team will be
assigned a small project to
finish before oral
presentation; that is, each
team must submit a written
report (hard copy) and a
powerpoint electronic file
for oral presentation to
Professor Fang by November
14. The written report must
include description of each
slide presented in the
powerpoint file.
b Only 4 teams will be
selected for 20-minute oral
presentation, and other 4
teams will be selected for
giving 3-minute comments
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
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參考書目 |
McMurry, John; Begley, Tadhg P. The organic chemistry of
biological pathways, Roberts and Co. Publishers:
Englewood, Colorado, 2005.
Robert A. Copeland, Evaluation of Enzyme Inhibitors in
Drug Discovery; Wiley: 2005. |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
期中考 |
35% |
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2. |
期末考 |
50% |
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3. |
隨堂測驗 |
0% |
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4. |
作業 |
0% |
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5. |
報告 |
15% |
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週次 |
日期 |
單元主題 |
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第1週 |
9/17,9/19 |
Molecules of Life |
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第2週 |
9/24,9/26 |
Molecules of Life |
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第3週 |
10/01,10/03 |
Molecules of Life |
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第4週 |
10/08,10/10 |
Molecules of Life |
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第5週 |
10/15,10/17 |
Structural Determination and Sequencing of Biomolecules |
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第6週 |
10/22,10/24 |
Structural Determination and Sequencing of Biomolecules |
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第7週 |
10/29,10/31 |
Structural Determination and Sequencing of Biomolecules |
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第8週 |
11/05,11/07 |
Structural Determination and Sequencing of Biomolecules |
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第9週 |
11/12,11/14 |
Structural Determination and Sequencing of Biomolecules |
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第11週 |
11/26,11/28 |
Midterm Exam |
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第12週 |
12/03,12/05 |
Enzyme Mechanism and Function |
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第13週 |
12/10,12/12 |
Enzyme Mechanism and Function |
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第14週 |
12/17,12/19 |
Enzyme Mechanism and Function |
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第15週 |
12/24,12/26 |
Enzyme Mechanism and Function |
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第16週 |
12/31,1/02 |
Enzyme Mechanism and Function |
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第17週 |
1/07,1/09 |
Enzyme Mechanism and Function |
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